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AZD1152 rapidly and negatively affects the growth and survival of Human AML cells in vitro and in vivo
Aurora kinases play a critical role in regulating mitosis and cell division and there over expression have been implicated in the survival and proliferation of human cancer. In this study we report the in vitro and in vivo activities of AZD1152, a compound that has selectivity for aurora B kinase, i...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684546/ https://ncbi.nlm.nih.gov/pubmed/19366807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3203 |
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