AML engraftment in the NOD/SCID assay reflects the outcome of AML: implications for our understanding of the heterogeneity of AML

The nonobese diabetic/severe combined immunodeficient (NOD/SCID) assay is the current model for assessment of human normal and leukemic stem cells. We explored why 51% of 59 acute myeloid leukemia (AML) patients were unable to initiate leukemia in NOD/SCID mice. Increasing the cell dose, using more...

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Main Authors: Pearce, Daniel J., Taussig, David, Zibara, Kazem, Smith, Lan-Lan, Ridler, Christopher M., Preudhomme, Claude, Young, Bryan D., Rohatiner, Ama Z., Lister, T. Andrew, Bonnet, Dominique
格式: Artigo
語言:Inglês
出版: © 2006 by The American Society of Hematology 2006
主題:
Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895911/
https://ncbi.nlm.nih.gov/pubmed/16234360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2325
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