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CD123 AML targeting by chimeric antigen receptors: A novel magic bullet for AML therapeutics?

Chimeric antigen receptor (CAR) modified T cells have emerged as powerful tools for controlling leukemias. We recently showed that anti-CD123 CAR-expressing cytokine-induced killer T cell treatment is an effective immunotherapeutic approach to eradicate Acute Myeloid Leukemia (AML) cells. Here, we d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tettamanti, Sarah, Biondi, Andrea, Biagi, Ettore, Bonnet, Dominique
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106165/
https://ncbi.nlm.nih.gov/pubmed/25083319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28835
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