Endoglin Expression in Blood and Endothelium is Differentially Regulated by Modular Assembly of the Ets/Gata Hemangioblast Code

Endoglin is an accessory receptor for TGF-β signalling and is required for normal hemangioblast, early hematopoietic and vascular development. We have previously shown that an upstream enhancer, Eng-8 together with the promoter region mediates robust endothelial expression yet is inactive in blood....

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Hauptverfasser: Pimanda, John E., Chan, Wan Y.I., Wilson, Nicola K., Smith, Aileen M., Kinston, Sarah, Knezevic, Kathy, Janes, Mary E., Landry, Josette-Renée, Kolb-Kokocinski, Anja, Frampton, Jonathan, Tannahill, David, Ottersbach, Katrin, Follows, George A., Lacaud, Georges, Kouskoff, Valerie, Göttgens, Berthold
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682356/
https://ncbi.nlm.nih.gov/pubmed/18805961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-157560
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