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Induction of Alpha/Beta Interferon by Myxoma Virus Is Selectively Abrogated When Primary Mouse Embryo Fibroblasts Become Immortalized

Mouse embryo fibroblasts (MEFs) are a widely used cell culture system in life sciences, including virology. Here, we show that although primary MEFs are nonpermissive to myxoma virus replication, the corresponding immortalized MEFs support a highly productive myxoma virus infection. We further demon...

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Bibliografische gegevens
Hoofdauteurs: Wang, Fuan, Barrett, John W., Ma, Yiyue, Dekaban, Gregory A., McFadden, Grant
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681981/
https://ncbi.nlm.nih.gov/pubmed/19297474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02587-08
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