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M135R Is a Novel Cell Surface Virulence Factor of Myxoma Virus

Myxoma virus (MV) encodes a cell surface protein (M135R) that is predicted to mimic the host alpha/beta interferon receptor (IFN-α/β-R) and thus prevent IFN-α/β from triggering a host antiviral response. This prediction is based on sequence similarity to B18R, the viral IFN-α/β-R from vaccinia virus...

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Autori principali: Barrett, John W., Sypula, Joanna, Wang, Fuan, Alston, Lindsay R., Shao, Zhuhong, Gao, Xiujuan, Irvine, Timothy S., McFadden, Grant
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797242/
https://ncbi.nlm.nih.gov/pubmed/17065210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01633-06
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