RIG-I Mediates the Co-Induction of Tumor Necrosis Factor and Type I Interferon Elicited by Myxoma Virus in Primary Human Macrophages

The sensing of pathogen infection and subsequent triggering of innate immunity are key to controlling zoonotic infections. Myxoma virus (MV) is a cytoplasmic DNA poxvirus that in nature infects only rabbits. Our previous studies have shown that MV infection of primary mouse cells is restricted by vi...

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Hauptverfasser: Wang, Fuan, Gao, Xiujuan, Barrett, John W., Shao, Qing, Bartee, Eric, Mohamed, Mohamed R., Rahman, Masmudur, Werden, Steve, Irvine, Timothy, Cao, Jingxin, Dekaban, Gregory A., McFadden, Grant
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438611/
https://ncbi.nlm.nih.gov/pubmed/18617992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000099
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