Myxoma Virus Expressing Human Interleukin-12 Does Not Induce Myxomatosis in European Rabbits

Myxoma virus (MV) is a candidate for oncolytic virotherapy due to its ability to selectively infect and kill tumor cells, yet MV is a species-specific pathogen that causes disease only in European rabbits. To assess the ability of MV to deliver cytokines to tumors, we created an MV (vMyxIL-12) that...

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Detalhes bibliográficos
Main Authors: Stanford, Marianne M., Barrett, John W., Gilbert, Philippe-Alexandre, Bankert, Richard, McFadden, Grant
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168987/
https://ncbi.nlm.nih.gov/pubmed/17728229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01483-07
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