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Myxoma Virus Expressing Interleukin-15 Fails To Cause Lethal Myxomatosis in European Rabbits

Myxoma virus (MYXV) is a poxvirus pathogenic only for European rabbits, but its permissiveness in human cancer cells gives it potential as an oncolytic virus. A recombinant MYXV expressing both the tdTomato red fluorescent protein and interleukin-15 (IL-15) (vMyx-IL-15-tdTr) was constructed. Cells i...

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Detalhes bibliográficos
Main Authors: Liu, Jia, Wennier, Sonia, Reinhard, Mary, Roy, Edward, MacNeill, Amy, McFadden, Grant
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681933/
https://ncbi.nlm.nih.gov/pubmed/19279088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00204-09
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