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The immunoregulatory properties of oncolytic myxoma virus and their implications in therapeutics
Myxoma virus (MYXV) is a poxvirus with a strict rabbit-specific host-tropism for pathogenesis. The immunoregulatory factors encoded by MYXV can suppress some functions of immune effectors from other species. We review their mechanisms of action, implications in therapeutics and the potential to impr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998584/ https://ncbi.nlm.nih.gov/pubmed/20832500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2010.08.012 |
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