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Myxoma Virus Sensitizes Cancer Cells to Gemcitabine and Is an Effective Oncolytic Virotherapeutic in Models of Disseminated Pancreatic Cancer

Myxoma virus (MYXV) is a novel oncolytic virus that has been shown to replicate in pancreatic cancer cells, but its efficacy in animal models of pancreatic cancer has not been determined. The efficacy of MYXV as monotherapy or in combination with gemcitabine was evaluated in intraperitoneal dissemin...

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Detalhes bibliográficos
Main Authors: Wennier, Sonia Tusell, Liu, Jia, Li, Shoudong, Rahman, Masmudur M., Mona, Mahmoud, McFadden, Grant
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321583/
https://ncbi.nlm.nih.gov/pubmed/22233582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.293
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