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Pharmacological Manipulation of the Akt Signaling Pathway Regulates Myxoma Virus Replication and Tropism in Human Cancer Cells

Viruses have evolved an assortment of mechanisms for regulating the Akt signaling pathway to establish a cellular environment more favorable for viral replication. Myxoma virus (MYXV) is a rabbit-specific poxvirus that encodes many immunomodulatory factors, including an ankyrin repeat-containing hos...

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Détails bibliographiques
Auteurs principaux: Werden, Steven J., McFadden, Grant
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838123/
https://ncbi.nlm.nih.gov/pubmed/20106927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02020-09
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