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Asc and Ipaf Inflammasomes Direct Distinct Pathways for Caspase-1 Activation in Response to Legionella pneumophila

Caspase-1 activation is a key feature of the innate immune response of macrophages elicited by pathogens and a variety of toxins. Here, we determined the requirement for different adapter proteins involved in regulating host processes mediated by caspase-1 after macrophage infection by Legionella pn...

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Detalhes bibliográficos
Main Authors: Case, Christopher L., Shin, Sunny, Roy, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681768/
https://ncbi.nlm.nih.gov/pubmed/19237518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01382-08
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