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Host-Dependent Trigger of Caspases and Apoptosis by Legionella pneumophila
The Dot/Icm system of Legionella pneumophila triggers activation of caspase-3 during early stages of infection of human macrophages, but apoptosis is delayed until late stages of infection. During early stages of infection of mouse macrophages, the organism triggers rapid caspase-1-mediated cytotoxi...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1932860/ https://ncbi.nlm.nih.gov/pubmed/17420236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00147-07 |
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