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Host-Dependent Trigger of Caspases and Apoptosis by Legionella pneumophila

The Dot/Icm system of Legionella pneumophila triggers activation of caspase-3 during early stages of infection of human macrophages, but apoptosis is delayed until late stages of infection. During early stages of infection of mouse macrophages, the organism triggers rapid caspase-1-mediated cytotoxi...

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Autors principals: Santic, Marina, Asare, Rexford, Doric, Miljenko, Abu Kwaik, Yousef
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932860/
https://ncbi.nlm.nih.gov/pubmed/17420236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00147-07
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