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The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance
Tagging a small molecule ubiquitin to a protein substrate, or protein ubiquitination, plays an important role in the immune responses. This process is catalyzed by a cascade of enzymatic reactions, with the E3 ubiquitin ligases being the critical enzymes that determine the specificity of substrate r...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680672/ https://ncbi.nlm.nih.gov/pubmed/17433711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2007.02.003 |
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