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Foxp3 positive regulatory T cells: a functional regulation by the E3 ubiquitin ligase Itch
Regulatory T cells (Tregs) play a critical role in maintaining immune tolerance to self-antigens, whose development and activation is controlled by the master regulator and transcription factor Foxp3. Foxp3 acts as transcription repressor and exerts its suppressing function via directly associating...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2868094/ https://ncbi.nlm.nih.gov/pubmed/20108139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-009-0192-1 |
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