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Foxp3 positive regulatory T cells: a functional regulation by the E3 ubiquitin ligase Itch

Regulatory T cells (Tregs) play a critical role in maintaining immune tolerance to self-antigens, whose development and activation is controlled by the master regulator and transcription factor Foxp3. Foxp3 acts as transcription repressor and exerts its suppressing function via directly associating...

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Detalhes bibliográficos
Main Authors: Su, Jin, Liu, Yun-Cai
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868094/
https://ncbi.nlm.nih.gov/pubmed/20108139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-009-0192-1
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