Hierarchical Regulation of WASP/WAVE Proteins

Members of the Wiskott-Aldrich Syndrome Protein (WASP) family control actin dynamics in eukaryotic cells through stimulating the actin nucleating activity of the Arp2/3 complex. The prevailing paradigm for WASP regulation invokes allosteric relief of autoinhibition by diverse upstream activators. He...

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Main Authors: Padrick, Shae B., Cheng, Hui-Chun, Ismail, Ayman M., Panchal, Sanjay C., Doolittle, Lynda K., Kim, Soyeon, Skehan, Brian M., Umetani, Junko, Brautigam, Chad A., Leong, John M., Rosen, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680354/
https://ncbi.nlm.nih.gov/pubmed/18995840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.10.012
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