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The WAVE Regulatory Complex is Inhibited
The WAVE Regulatory Complex (WRC) transmits information from the Rac GTPase to the actin nucleator, Arp2/3 complex. We have reconstituted recombinant human and Drosophila WRC in several forms and shown that they are inactive toward Arp2/3 complex, but can be activated by Rac in nucleotide dependent...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716658/ https://ncbi.nlm.nih.gov/pubmed/19363480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1587 |
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