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Arp2/3 complex is bound and activated by two WASP proteins

Actin related protein 2/actin related protein 3 (Arp2/3) complex nucleates new actin filaments in eukaryotic cells in response to signals from proteins in the Wiskott–Aldrich syndrome protein (WASP) family. The conserved VCA domain of WASP proteins activates Arp2/3 complex by inducing conformational...

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Detalhes bibliográficos
Main Authors: Padrick, Shae B., Doolittle, Lynda K., Brautigam, Chad A., King, David S., Rosen, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158169/
https://ncbi.nlm.nih.gov/pubmed/21676863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100236108
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