Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation

During cell locomotion and endocytosis, membrane-tethered WASP proteins stimulate actin filament nucleation by the Arp2/3 complex. This process generates highly branched arrays of filaments that grow toward the membrane to which they are tethered, a conflict that seemingly would restrict filament gr...

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Detalles Bibliográficos
Autores principales: Smith, Benjamin A, Padrick, Shae B, Doolittle, Lynda K, Daugherty-Clarke, Karen, Corrêa, Ivan R, Xu, Ming-Qun, Goode, Bruce L, Rosen, Michael K, Gelles, Jeff
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biochemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762362/
https://ncbi.nlm.nih.gov/pubmed/24015360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01008
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