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Physical Mechanisms of Signal Integration by WASP Family Proteins

The proteins of the Wiskott-Aldrich Syndrome protein (WASP) family are activators of the ubiquitous actin nucleation factor, Arp2/3 complex. WASP family proteins contain a C-terminal VCA domain that binds and activates Arp2/3 complex in response to numerous inputs, including Rho family GTPases, phos...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Padrick, Shae B., Rosen, Michael K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017724/
https://ncbi.nlm.nih.gov/pubmed/20533885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biochem.77.060407.135452
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