Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation

Integrins are the major adhesion receptors of leukocytes and platelets. β(1) and β(2) integrin function on leukocytes is crucial for a successful immune response and the platelet integrin α(IIb)β(3) initiates the process of blood clotting through binding fibrinogen1-3. Integrins on circulating cells...

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Detaylı Bibliyografya
Asıl Yazarlar: Svensson, Lena, Howarth, Kimberley, McDowall, Alison, Patzak, Irene, Evans, Rachel, Ussar, Siegfried, Moser, Markus, Metin, Ayse, Fried, Mike, Tomlinson, Ian, Hogg, Nancy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680140/
https://ncbi.nlm.nih.gov/pubmed/19234463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1931
Etiketler: Etiketle
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