G Protein-Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure

Myocardial G protein-coupled receptor kinase 2 (GRK2) is a critical regulator of cardiac β-adrenergic receptor (βAR) signaling and cardiac function. Its upregulation in heart failure (HF) may further depress cardiac function and contribute to mortality in this syndrome. Preventing GRK2 translocation...

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書誌詳細
主要な著者: Raake, Philip W., Vinge, Leif E., Gao, Erhe, Boucher, Matthieu, Chen, Xiongwen, DeGeorge, Brent R., Matkovich, Scot, Houser, Steven R., Most, Patrick, Eckhart, Andrea D., Dorn, Gerald W., Koch, Walter J.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679955/
https://ncbi.nlm.nih.gov/pubmed/18635825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.168336
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