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G Protein-Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure
Myocardial G protein-coupled receptor kinase 2 (GRK2) is a critical regulator of cardiac β-adrenergic receptor (βAR) signaling and cardiac function. Its upregulation in heart failure (HF) may further depress cardiac function and contribute to mortality in this syndrome. Preventing GRK2 translocation...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679955/ https://ncbi.nlm.nih.gov/pubmed/18635825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.168336 |
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