Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes

G protein-coupled receptor (GPCR) kinases (GRKs) are critical regulators of cellular signaling and function. In cardiomyocytes, GRK2 and GRK5 are two GRKs important for myocardial regulation, and both have been shown to be up-regulated in the dysfunctional heart. We report that increased levels and...

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Detaylı Bibliyografya
Asıl Yazarlar: Martini, Jeffrey S., Raake, Philip, Vinge, Leif E., DeGeorge, Brent R., Chuprun, J. Kurt, Harris, David M., Gao, Erhe, Eckhart, Andrea D., Pitcher, Julie A., Koch, Walter J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527933/
https://ncbi.nlm.nih.gov/pubmed/18711143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803153105
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