Regulation of Nuclear Factor κB (NF-κB) in the Nucleus of Cardiomyocytes by G Protein-coupled Receptor Kinase 5 (GRK5)

G protein-coupled receptor kinase 5 GRK5 plays a key role in regulating cardiac signaling and its expression is increased in heart failure. GRK5 activity in the nucleus of myocytes has been shown to be detrimental in the setting of pressure-overload hypertrophy. The ubiquitous nuclear transcription...

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Bibliographic Details
Main Authors: Islam, Kazi N., Bae, Jang-Whan, Gao, Erhe, Koch, Walter J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861620/
https://ncbi.nlm.nih.gov/pubmed/24174526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529347
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