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Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): A strategy for vascular immunotargeting of drugs
Conjugation of drugs with antibodies to surface endothelial antigens is a potential strategy for drug delivery to endothelium. We studied antibodies to platelet-endothelial adhesion molecule 1 (PECAM-1, a stably expressed endothelial antigen) as carriers for vascular immunotargeting. Although (125)I...
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Главные авторы: | , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
The National Academy of Sciences
1999
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC26792/ https://ncbi.nlm.nih.gov/pubmed/10051650 |
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