Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development

NFAT transcription factors are highly phosphorylated proteins residing in the cytoplasm of resting cells. Upon dephosphorylation by the phosphatase calcineurin, NFAT proteins translocate to the nucleus, where they orchestrate developmental and activation programs in diverse cell types. NFAT is repho...

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Hauptverfasser: Müller, Martin R., Sasaki, Yoshiteru, Stevanovic, Irena, Lamperti, Edward D., Ghosh, Srimoyee, Sharma, Sonia, Gelinas, Curtis, Rossi, Derrick J., Pipkin, Matthew E., Rajewsky, Klaus, Hogan, Patrick G., Rao, Anjana
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678457/
https://ncbi.nlm.nih.gov/pubmed/19351896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813296106
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