Hair Loss and Defective T- and B-Cell Function in Mice Lacking ORAI1

ORAI1 is a pore subunit of the store-operated Ca(2+) release-activated Ca(2+) (CRAC) channel. To examine the physiological consequences of ORAI1 deficiency, we generated mice with targeted disruption of the Orai1 gene. The results of immunohistochemical analysis showed that ORAI1 is expressed in lym...

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Detalhes bibliográficos
Main Authors: Gwack, Yousang, Srikanth, Sonal, Oh-hora, Masatsugu, Hogan, Patrick G., Lamperti, Edward D., Yamashita, Megumi, Gelinas, Curtis, Neems, Daniel S., Sasaki, Yoshiteru, Feske, Stefan, Prakriya, Murali, Rajewsky, Klaus, Rao, Anjana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519726/
https://ncbi.nlm.nih.gov/pubmed/18591248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00360-08
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