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Store-operated Ca(2+) entry through ORAI1 is critical for T cell mediated autoimmunity and allograft rejection
ORAI1 is the pore forming subunit of the Ca(2+) release activated Ca(2+) (CRAC) channel, which is responsible for store-operated Ca(2+) entry (SOCE) in lymphocytes. A role for ORAI1 in T cell function in vivo has been inferred from in vitro studies of T cells from human immunodeficient patients with...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974040/ https://ncbi.nlm.nih.gov/pubmed/20956344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001796 |
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