ORAI2 modulates store-operated calcium entry and T cell-mediated immunity

Store-operated Ca(2+) entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels is critical for lymphocyte function and immune responses. CRAC channels are hexamers of ORAI proteins that form the channel pore, but the contributions of individual ORAI homologues to CRAC channel function ar...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Vaeth, Martin, Yang, Jun, Yamashita, Megumi, Zee, Isabelle, Eckstein, Miriam, Knosp, Camille, Kaufmann, Ulrike, Karoly Jani, Peter, Lacruz, Rodrigo S., Flockerzi, Veit, Kacskovics, Imre, Prakriya, Murali, Feske, Stefan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355949/
https://ncbi.nlm.nih.gov/pubmed/28294127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14714
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