ORAI2 modulates store-operated calcium entry and T cell-mediated immunity

Store-operated Ca(2+) entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels is critical for lymphocyte function and immune responses. CRAC channels are hexamers of ORAI proteins that form the channel pore, but the contributions of individual ORAI homologues to CRAC channel function ar...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Vaeth, Martin, Yang, Jun, Yamashita, Megumi, Zee, Isabelle, Eckstein, Miriam, Knosp, Camille, Kaufmann, Ulrike, Karoly Jani, Peter, Lacruz, Rodrigo S., Flockerzi, Veit, Kacskovics, Imre, Prakriya, Murali, Feske, Stefan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355949/
https://ncbi.nlm.nih.gov/pubmed/28294127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14714
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