Loading...

Structural basis for cAMP-mediated allosteric control of the catabolite activator protein

The cAMP-mediated allosteric transition in the catabolite activator protein (CAP; also known as the cAMP receptor protein, CRP) is a textbook example of modulation of DNA-binding activity by small-molecule binding. Here we report the structure of CAP in the absence of cAMP, which, together with stru...

Full description

Saved in:
Bibliographic Details
Main Authors: Popovych, Nataliya, Tzeng, Shiou-Ru, Tonelli, Marco, Ebright, Richard H., Kalodimos, Charalampos G.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678429/
https://ncbi.nlm.nih.gov/pubmed/19359484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900595106
Tags: Add Tag
No Tags, Be the first to tag this record!