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Structural basis for cAMP-mediated allosteric control of the catabolite activator protein
The cAMP-mediated allosteric transition in the catabolite activator protein (CAP; also known as the cAMP receptor protein, CRP) is a textbook example of modulation of DNA-binding activity by small-molecule binding. Here we report the structure of CAP in the absence of cAMP, which, together with stru...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
National Academy of Sciences
2009
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678429/ https://ncbi.nlm.nih.gov/pubmed/19359484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900595106 |
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