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Dynamically driven protein allostery

Allosteric interactions are typically considered to proceed through a series of discrete changes in bonding interactions that alter the protein conformation. Here we show that allostery can be mediated exclusively by transmitted changes in protein motions. We have characterized the negatively cooper...

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Detalhes bibliográficos
Main Authors: Popovych, Nataliya, Sun, Shangjin, Ebright, Richard H., Kalodimos, Charalampos G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757644/
https://ncbi.nlm.nih.gov/pubmed/16906160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1132
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