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Dynamically driven protein allostery
Allosteric interactions are typically considered to proceed through a series of discrete changes in bonding interactions that alter the protein conformation. Here we show that allostery can be mediated exclusively by transmitted changes in protein motions. We have characterized the negatively cooper...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757644/ https://ncbi.nlm.nih.gov/pubmed/16906160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1132 |
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