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LIP5 Interacts with Aquaporin 2 and Facilitates Its Lysosomal Degradation
Vasopressin binding to the V2 receptor in renal principal cells leads to activation of protein kinase A, phosphorylation of aquaporin 2 (AQP2) at Ser256, and the translocation of AQP2 to the apical membrane, resulting in concentration of the urine. In contrast, phorbol ester–induced activation of pr...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Nephrology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678037/ https://ncbi.nlm.nih.gov/pubmed/19357255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008060648 |
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