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Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel

To regulate mammalian water homeostasis, arginine-vasopressin (AVP) induces phosphorylation and thereby redistribution of renal aquaporin-2 (AQP2) water channels from vesicles to the apical membrane. Vice versa, AVP (or forskolin) removal and hormones activating PKC cause AQP2 internalization, but t...

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Detalhes bibliográficos
Main Authors: Kamsteeg, Erik-Jan, Hendriks, Giel, Boone, Michelle, Konings, Irene B. M., Oorschot, Viola, van der Sluijs, Peter, Klumperman, Judith, Deen, Peter M. T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838753/
https://ncbi.nlm.nih.gov/pubmed/17101973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604073103
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