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RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter
The sodium-chloride cotransporter (NCC) is the principal salt-absorptive pathway in the distal convoluted tubule. Recently, we described a novel pathway of NCC regulation in which phorbol esters (PE) stimulate Ras guanyl-releasing protein 1 (RasGRP1), triggering a cascade ultimately activating ERK1/...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928521/ https://ncbi.nlm.nih.gov/pubmed/20392800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00441.2009 |
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