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Forced expression of AID facilitates the isolation of class switch variants from hybridoma cells

Monoclonal antibodies are used in the treatment and diagnosis of diseases and to study the protective and adverse functions of antibodies in vitro and in vivo. Since the isotype determines the effector function, half-life in the serum and distribution throughout the body, it would be useful to have...

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Bibliografiska uppgifter
Huvudupphovsmän: Iglesias-Ussel, Maria D., Fan, Manxia, Li, Ziqiang, Martin, Alberto, Scharff, Matthew D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677521/
https://ncbi.nlm.nih.gov/pubmed/16997317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2006.08.002
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