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Forced expression of AID facilitates the isolation of class switch variants from hybridoma cells
Monoclonal antibodies are used in the treatment and diagnosis of diseases and to study the protective and adverse functions of antibodies in vitro and in vivo. Since the isotype determines the effector function, half-life in the serum and distribution throughout the body, it would be useful to have...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677521/ https://ncbi.nlm.nih.gov/pubmed/16997317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2006.08.002 |
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