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Molecular characterization of hybridoma subclones spontaneously switching at high frequencies in vitro

The hybridoma technology allows the production of large quantities of specific antibodies of a single isotype. Since different isotypes have special effector functions and are distributed distinctively throughout the body, it is often useful to have a library of switch variants from the original mon...

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Detalhes bibliográficos
Main Authors: Iglesias-Ussel, Maria D., Zavadil, Jiri, Scharff, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762006/
https://ncbi.nlm.nih.gov/pubmed/19619554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2009.07.003
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