טוען...
The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity
WTX encodes a tumor suppressor gene inactivated in Wilms tumor and recently implicated in WNT signaling through enhancement of cytoplasmic β-catenin (CTNNB1) degradation. Here, we report that WTX translocates to the nucleus, a property that is modified by an endogenous splicing variant and is modula...
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| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677091/ https://ncbi.nlm.nih.gov/pubmed/19416806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811349106 |
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