Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis

CCAAT/enhancer binding protein alpha (CEBPA) mutations in AML are associated with favourable prognosis and are divided into N- and C-terminal mutations. The majority of AML patients have both types of mutations. We assessed the prognostic significance of single (n=7) and double (n=12) CEBPA mutation...

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Bibliographic Details
Main Authors: Pabst, T, Eyholzer, M, Fos, J, Mueller, B U
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
Subjects:
Genetics and Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676545/
https://ncbi.nlm.nih.gov/pubmed/19277035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604977
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