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Identification of novel CEBPA double mutations capable of promoting familial AML via the suppression of myeloid differentiation

CCAAT-enhancer-binding protein α (CEBPA) gene carrying two mutations (CEBPA double mutations) is known to promote familial acute myeloid leukemia (AML). However, the underlying mechanism by which CEBPA double mutations promote AML remains poorly understood. Here we report that a family with three ge...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zheng, Yunjing, Zhang, Hui, Lu, Qin, Chu, Xinran, Gao, Li, Xiao, Peifang, Pan, Jian, Hu, Shaoyan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653564/
https://ncbi.nlm.nih.gov/pubmed/33194086
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