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Knockdown of m-calpain increases survival of primary hippocampal neurons following NMDA excitotoxicity

The calpain family of cysteine proteases has a well-established causal role in neuronal cell death following acute brain injury. However, the relative contribution of calpain isoforms to the various forms of injury has not been determined as available calpain inhibitors are not isoform-specific. In...

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Detalhes bibliográficos
Main Authors: Bevers, Matthew B., Lawrence, Eric, Maronski, Margaret, Starr, Neasa, Amesquita, Michael, Neumar, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676331/
https://ncbi.nlm.nih.gov/pubmed/19141074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05860.x
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