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RNAi targeting μ-calpain increases neuron survival and preserves hippocampal function after global brain ischemia
The calpain family of cysteine proteases has a well-established causal role in neuronal cell death following acute brain injury. However, the relative contribution of calpain isoforms has not been determined in in vivo models. Identification of the calpain isoform responsible for neuronal injury is...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885584/ https://ncbi.nlm.nih.gov/pubmed/20298691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.03.007 |
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