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Neuroprotection with Delayed Calpain Inhibition after Transient Forebrain Ischemia

OBJECTIVE: Delayed neurodegeneration after transient global brain ischemia offers a therapeutic window for inhibiting molecular injury mechanisms. One such mechanism is calpain-mediated proteolysis, which peaks 24 to 48 hours after transient forebrain ischemia in rats. This study tests the hypothesi...

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Detalhes bibliográficos
Main Authors: Frederick, James R., Chen, Zhaoming, Bevers, Matthew B., Ingleton, Lori P., Ma, Marek, Neumar, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867247/
https://ncbi.nlm.nih.gov/pubmed/20449914
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