RNAi targeting μ-calpain increases neuron survival and preserves hippocampal function after global brain ischemia

The calpain family of cysteine proteases has a well-established causal role in neuronal cell death following acute brain injury. However, the relative contribution of calpain isoforms has not been determined in in vivo models. Identification of the calpain isoform responsible for neuronal injury is...

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Detaylı Bibliyografya
Asıl Yazarlar: Bevers, Matthew B., Ingleton, Lori P., Che, Dongfang, Li, Luchuan, Da, Tong, Kopil, Catherine M., Cohen, Akiva S., Neumar, Robert W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885584/
https://ncbi.nlm.nih.gov/pubmed/20298691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.03.007
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