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Reactive Oxygen Species Are Not Required for an Arsenic Trioxide-induced Antioxidant Response or Apoptosis

Arsenicals are both environmental carcinogens as well as therapeutic agents for the treatment of trypanosomiasis and more recently cancer. Arsenic trioxide (ATO) has been successfully used for the treatment of acute promyelocytic leukemia (APL) and has activity in multiple myeloma (MM). While signal...

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Autori principali: Morales, Alejo A., Gutman, Delia, Cejas, Pedro J., Lee, Kelvin P., Boise, Lawrence H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676019/
https://ncbi.nlm.nih.gov/pubmed/19279006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806546200
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