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Reactive Oxygen Species Are Not Required for an Arsenic Trioxide-induced Antioxidant Response or Apoptosis

Arsenicals are both environmental carcinogens as well as therapeutic agents for the treatment of trypanosomiasis and more recently cancer. Arsenic trioxide (ATO) has been successfully used for the treatment of acute promyelocytic leukemia (APL) and has activity in multiple myeloma (MM). While signal...

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Detalhes bibliográficos
Main Authors: Morales, Alejo A., Gutman, Delia, Cejas, Pedro J., Lee, Kelvin P., Boise, Lawrence H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676019/
https://ncbi.nlm.nih.gov/pubmed/19279006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806546200
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