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Arsenic trioxide induces apoptosis and the formation of reactive oxygen species in rat glioma cells

BACKGROUND: Arsenic trioxide (As(2)O(3)) has a dramatic therapeutic effect on acute promyelocytic leukemia (APL) patients. It can also cause apoptosis in various tumor cells. This study investigated whether As(2)O(3) has an antitumor effect on glioma and explored the underlying mechanism. RESULTS: M...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Sun, Yuanyuan, Wang, Chen, Wang, Ligang, Dai, Zhibo, Yang, Kongbin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870496/
https://ncbi.nlm.nih.gov/pubmed/29610575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-018-0074-4
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