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BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide–induced cell death in myeloma

The use of arsenic trioxide (ATO) to treat multiple myeloma (MM) is supported by preclinical studies as well as several phase 2 studies, but the precise mechanism(s) of action of ATO has not been completely elucidated. We used gene expression profiling to determine the regulation of apoptosis-relate...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Morales, Alejo A., Gutman, Delia, Lee, Kelvin P., Boise, Lawrence H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384139/
https://ncbi.nlm.nih.gov/pubmed/18354037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-116889
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