טוען...

BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide–induced cell death in myeloma

The use of arsenic trioxide (ATO) to treat multiple myeloma (MM) is supported by preclinical studies as well as several phase 2 studies, but the precise mechanism(s) of action of ATO has not been completely elucidated. We used gene expression profiling to determine the regulation of apoptosis-relate...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Morales, Alejo A., Gutman, Delia, Lee, Kelvin P., Boise, Lawrence H.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384139/
https://ncbi.nlm.nih.gov/pubmed/18354037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-116889
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