Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin–proteasomal degradation

Small Heterodimer Partner (SHP) inhibits activities of numerous transcription factors involved in diverse biological pathways. As an important metabolic regulator, SHP plays a key role in maintaining cholesterol and bile acid homeostasis by inhibiting cholesterol conversion to bile acids. While SHP...

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Main Authors: Miao, Ji, Xiao, Zhen, Kanamaluru, Deepthi, Min, Gyesik, Yau, Peter M., Veenstra, Timothy D., Ellis, Ewa, Strom, Steve, Suino-Powell, Kelly, Xu, H. Eric, Kemper, Jongsook Kim
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2009
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675865/
https://ncbi.nlm.nih.gov/pubmed/19390091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1773909
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